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Effective dosing ranged between 0.25 and 2.0 mg/kg/day ( The serotonergic 5-HT 4 receptor agonist, cisapride, was associated with symptomatic benefit in patients with gastroparesis based on short-or medium-term placebo-controlled trials (Richards et al., 1993a), and on long-term, open-label studies ( Other medications available in a few countries, clebopride, cinitapride, and mosapride, are not reviewed in detail here in view of the relatively weak evidence of efficacy in gastroparesis

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